|
KMID : 0352819880040010093
|
|
Kosin Medical Journal
1988 Volume.4 No. 1 p.93 ~ p.100
|
|
|
THE EFFECTS OF MIIUNE RAT SERUM ON CLONORCHIS SINENSIS IN VITRO
|
|
Ock, Mee Sun
|
|
|
Abstract
|
|
|
The present study was performed to clarify the effect of immune rat serum on Clonorchis sinensis, liver fluke, adult worms, excysted juvenile worms, metacercariae, and eggs in vitro.
The adult and juvenile C. sinensis incubated in infected rat serum (IRS) developed tegumental precipitate which seemed to have an effect on the viability of parasites. No such reactions were observed in normal rat serum (NRS). Metacercariae and eggs cultured in immune serum did not show the precipitate on tegument.
Heat inactivation of IRS at 56C, 30 min. diminished the precipitate dramatically on adult worts. But the ability of precipitate formation against adult worms regained upon addition of NRS.
From the results of the present study, it was suggested that the precipitate on tegument and in the medium have parasiticidal effects on C. sinensis adults and young worms, and is a specific immunoglobulin(s) and complement-dependent.
|
|
|
KEYWORD
|
|
|
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
|
|
|